About Us
The Siegelbaum lab studies how electrical signaling and synaptic plasticity in defined neural circuits processes information to encode social memory, an animal’s ability to recognize and recall another individual of its own species. We focus on the cortico-hippocampal circuit, and in particular on the CA2 region of the hippocampus. Our goal is to understand the neural mechanisms that enable an animal to distinguish a novel from familiar conspecific and to determine how alterations in this process may contribute to social dysfunction in neuropsychiatric disorders. We are located in the Jerome L. Greene Science Center of Columbia University and welcome postdoctoral, PhD student, and undergraduate researchers.
Recent Publication
A direct lateral entorhinal cortex to hippocampal CA2 circuit conveys social information required for social memory
News
Seeking Postdoctoral Scientist
Columbia's Zuckerman Institute is seeking a postdoctoral scientist to perform research using in vivo extracellular recordings and/or calcium imaging of hippocampal neuron activity in awake behaving mice.
Photos
lab members 2017
lab members 2023
The perineuronal net extracellular matrix of the hippocampal CA2 subfield
